THE 2-MINUTE RULE FOR METHADONE

Cost-free and conjugated noroxycodone, no cost and conjugated oxycodone, and oxymorphone are excreted in human urine pursuing one oral dose of oxycodone. The foremost circulating metabolite is noroxycodone with the AUC ratio of 0.six relative to that of oxycodone. Oxymorphone is current in the plasma only in very low concentrations. The analgesic a